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MS, NY, Nashville | Med Spa & Aesthetic Services Near You

Aesthetics Services


Car keys, iPhone, MIXTOHydrate. That’s the list of things I run through in my mind every time I leave the house. A week ago, I tried MIXTOHydrate for the first time and it immediately transformed my face.  My eyes were softened and fine lines were gone. Like gone, gone. My lips went from dry and slightly flaky to the plump bee-stung look I’ve been admiring in actress Margot Robbie (she played Leo DiCaprio’s wife in Wolf of Wall Street). I would say that it took years off my face but it was more than that. My skin was dewy, soft. It didn’t just LOOK younger, it WAS younger.

– Dr. Melissa Toyos

Why? To understand what makes MIXTOHydrate so special, it helps to know what is happening inside aging skin. One of the biggest changes that occurs in skin as it ages (and to a lesser extent in the winter or dry environments) is the loss of our skin’s ability to attract and retain moisture. As early as our 30s we slow our production of the hyaluronic acid and some amino acids that not only plump skin but act as a sponge, pulling water in and holding it there. Without it, our skin looks thinner, less “plump,” and dries out more easily. Hyaluronic acid can be replaced topically (it has been hard to get much in just by putting it on the skin). It is more easily put into the skin by injecting fillers like Juvederm to replace what has been lost.

Aging skin loses not only water content but also lipids and fat. Statistically, in our adult lives we lose about 65% of the lipids in our skin that were present in our twenties. This is not only a loss of volume or fat in our faces, but also a change in the character and texture of the skin so that skin is dryer, more prone to irritation, wrinkling, and looks less healthy, less “juicy.”.

Losing moisture content contributes to the overall thickness of skin which is the last characteristic we will discuss today. It is normal for skin to thin out progressively over your adult life. Thinner, less tight skin is prone to bruising and texture changes and is less capable of resisting gravity. The change of life with hormonal fluctuations and loss of estrogen dramatically accelerates this process. Thinning skin tends to be most noticeable in the face, neck, chest, hands, and forearms. We lose on average 6.4% of our total skin thickness with every passing decade. It only takes a few decades to really notice the changes.

So why is MIXTOHydrate different from every other moisturizer on the planet? MIXTOHydrate is the first moisturizer to pair acetyl-hexapeptide-37 and other peptides with hyaluronic acid to allow the hyaluronic acid to penetrate deeper into the skin than other products where it can hydrate the skin from the inside out. One application of MIXTOHydrate will more than double your skin hydration within 8 hours. Clinical studies show an unprecedented 131% increase in skin hydration 8 hours after using. With daily use, the same study showed that you can triple your skin’s moisture content within 56 days.

MIXTOHydrate also contains shea butter, squalene (natural lipid found in healthy young skin cells), and ceramides to lock in the moisture which results in long-lasting dewy, healthy complexions that have to be seen to be believed.

Harness the power of water to naturally replace and restore lost moisture in your skin. MIXTOHydrate is light enough to use every day under makeup and strong enough to use in the dead of winter to prevent dry, flaky, and deflated skin. One final tip: put it all over your face and watch specifically what it does to your eye area and to your lips.

Woman with water being thrown at her to show how hydrating the product is


As seen on TikTok! Created by our own Dr. Melissa Toyos in our compounding pharmacy, our 5% Copper topical skin cream has been proven to naturally boost collagen, elastin, and glycosaminoglycans like hyaluronic acid in the skin better than Retinol and better than Vitamin C without irritation and safe for all skin types. 

Woman with Blutox skin cream on her face


Bright is a high-potency combination of ingredients specifically addressing the needs of the eye area, combining protective antioxidants, soothing emollients, and firming peptides

Contains Tetrahexyldecyl ascorbate, the only non-acidic (safe for rosacea) Vitamin C compound clinically demonstrated in double-blind, placebo-controlled studies to increase both Grenz-zone and type-1 collagen. In addition to stimulating collagen production, this compound provides antioxidant protective activity, inhibits lipid peroxidation, and provides skin clarifying and brightening actions by lightening melanin granules. This antioxidant activity is supplemented by natural-source (d-stereoisomer) Vitamin E acetate and Green Tea: the mother of all antioxidants.

Contains Acetyl hexapeptide-8, a short-chain synthetic peptide that inhibits neurotransmitters responsible for cutaneous muscle contraction. Such inhibition results in muscle relaxation and smooths dynamic skin wrinkles.

Woman with Bright skin cream on her face



“I know this sounds weird, but I can’t quit touching my skin,” remarked the first patient to try our brand new Smooth moisturizer when it arrived. “My skin IS silky. It’s so soft and look,” she showed me, “my skin looks smoother and more even where put it compared to my other hand. ” Smooth is the latest addition to our highly potent iScience product line that people can’t stop talking about.

Made with a unique combination of naturally occurring skin moisturizers like ceramides, fatty acids, and naturally occurring cholesterol, Smooth replaces essential oils in the skin lost from age, harsh products, lack of proper hydration, and the environment

Enhanced with olive-derived squalene, Smooth restores the ideal moisture balance to dry, inflamed, and aging skin without fragrance or preservatives to make it safe for even the most sensitive of skin.

Smooth is recommended for use 1-3 times/day. I recommend that my patients use it more frequently until their skin drinks in as much as it needs before tapering. You can use Smooth under makeup, sunscreen, or even alone for a natural, dewy finish.

We’ve even sent the trifecta of moisturizers with our clients to the red carpet at the Oscars.

First, apply our iScience Plump – it is immediately absorbed into the skin. The hyaluronic acid acts as a sponge attracting and holding moisture and the peptides stimulate collagen production without irritation and also gently relax the wrinkles in a less obvious way than Botox. Chase it with the product that flies off our shelves, Hydrate. A creamier version of the highest molecular weight hyaluronic acid that can cross the skin barrier, it doubles your skin’s moisture content in 8 hours. Used daily, it triples your skin’s moisture in 2 months. Finally, apply Smooth to lock in all that juicy goodness and to give you a celebrity-like glow to your complexion.

iScience skincare line was developed by Dr. Melissa Toyos and has made a big splash internationally, on the carpets, and behind the ropes. You don’t have to walk the red carpet to look like you belong there. Come into Toyos Clinic to try them for yourself and to learn more about our product line.

Older woman using smooth skin cream


Contains Tetrahexyldecyl ascorbate, the only Vitamin C compound clinically demonstrated in double-blind, placebo-controlled studies to increase both Grenz-zone and type 1 collagen. In addition to stimulating collagen production, this compound provides antioxidant activity, inhibits lipid peroxidation, and provides skin clarifying and brightening actions by inhibiting melanogenesis

Contains natural-source Vitamin E Acetate (d-stereoisomer) and Green Tea Extract to help reduce skin dryness and irritation. Green Tea, the mother of all antioxidants, is a mixture of xanthine compounds (e.g. caffeine) and antioxidant (free radical scavenging) polyphenols

Non-acid formula is appropriate for individuals with sensitive skin, eye area application, rosacea, and after in-office procedures where the skin barrier may be compromised, such as microdermabrasion, chemical peels, and light-based treatments.

Two women with nice skin


Protect is an Anti-oxidant Facial Sunscreen that contains only hybrid sunblock Titanium and Zinc oxides in an elegant, anhydrous silicone elastomer vehicle that leaves a non-shiny, non-sticky mattifying film on the skin surface. Ideal daily facial photoprotection for patients with combination-to-oily complexions

Contains microencapsulated Melanin, Vitamins C, E and Ferulic acid ester for
enhanced antioxidant protection to absorb harmful UV rays before they reach the skin.

100% fragrance-free and preservative-free formula dries clear with a hint of color. For use alone or under makeup.

Women using protect skin cream

Polish Eye Treatment

Intensive, two-product regimen to transform aging sun-damaged skin. Combines a retinoid, peptides, anti-oxidants, and TCA. Improves the appearance of fine lines, wrinkles, puffiness, and dark circles. Good for night and day use and great for all skin types, except sensitive.

Women receiving polish eye treatment

Polish Facial Retexturing Cream

Provides retinoid benefits with less irritation, and antioxidant protection provided by Vitamin C + Vitamin E + Ferulic Acid ester, and anhydrous TCA. Great for night or day, or both. Specially designed for Dry/ Sensitive skin types. This is a transformative product for crepey, sun-damaged, aging skin, offering all the benefits of a chemical peel without the downtime.

Two women using the polish facial cream