Patients with dry eye and rosacea have roughly 20 times the normal amount of Demodex. Overgrowth of Demodex can lead to dry eye, meibomian gland dysfunction, and permanent changes in skin color and texture. Ivermectin has gained attention as a potential treatment for Demodex infestations, particularly in cases of Demodex-associated skin conditions such as rosacea and certain types of blepharitis. Demodex mites are microscopic parasites that inhabit human skin and hair follicles, coming out to do their dirty work at night. But Demodex are smart and can evade regular ivermectin which is why Toyos Clinic compounds their products with a special ingredient to attract and draw the Demodex mites in for additional efficacy.

Several studies have investigated the efficacy of ivermectin in treating Demodex infestations. One notable study published in the journal 'Dermatology' found that topical ivermectin was effective in reducing Demodex mite counts and improving symptoms in patients with rosacea. The study reported a significant decrease in both the number of mites and the severity of rosacea lesions following treatment with topical ivermectin.

Another study published in the 'International Journal of Infectious Diseases' evaluated the use of oral ivermectin in the treatment of Demodex-associated blepharitis, a condition characterized by inflammation of the eyelids. The researchers found that oral ivermectin was effective in reducing Demodex mite counts on the eyelids and improving symptoms such as itching, burning, and redness but topical is preferable to reduce systemic effects.

The mechanism of action of ivermectin against Demodex mites involves its ability to disrupt the nervous system of the parasites, leading to paralysis and death. This action makes ivermectin an effective treatment for eliminating Demodex infestations and alleviating associated symptoms.

Compared to other treatment options for Demodex infestations, such as topical metronidazole, ivermectin alone or permethrin, ivermectin has several advantages. It is highly effective at killing Demodex mites, has a low risk of resistance development, and is available in topical forms at Toyos Clinic for lids and skin.
Adverse effects such as skin irritation, itching, and allergic reactions can occur, and the Toyos formulation is specially created to reduce the risk of these effects.

Proper diagnosis and supervision by a healthcare provider are essential to ensure safe and effective use of ivermectin in the treatment of Demodex-associated skin disorders. If you would like to learn more, call 615.327.4015 or head to to schedule your personal consultation.